Biochemistry of Halogenated Organic Compounds by Kenneth L. Kirk

By Kenneth L. Kirk

Biochemistry of Halogenated natural Compounds has been written as a basic reference resource for researchers in different comparable components, together with natural chemists, medicinal chemists, pharmacologists, toxicologists, and clinical researchers. the advance of halogenated compounds as medicinal brokers and pharmacological instruments and the interesting biochemi­ cal tactics which have been came upon and studied utilizing those analogues have generated super lively components of study and a tremendous quantity of literature. hence, halogenated natural compounds pervade each point of biochemistry, a truth made obvious by way of the various reports and monographs on hand on person topics-halogenated nucleosides, halogenated carbohydrates, and so on. Given the volume of fabric already written on those themes, a few of which fabric is kind of present, it would be requested no matter if a one-volume evaluation of those matters turns out to be useful, or attainable. Having now accomplished this paintings, i believe the reply to either questions is an emphatic certain. There are interesting tales to be comparable in each one region, and, the place acceptable, i've got tried to strengthen those subject matters . from a ancient point of view. for instance, the invention of the anticancer job of fluorouracil, the unraveling of different mechanisms of its motion, and the improvement of a number of later generations of anticancer and antiviral brokers in line with the dad or mum fluoro-, iodo-, bromo-, and trifluoromethylpyrimidines have been, and are, contributions of significant importance to scientific science.

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